INS and Hyperglycemia: Physiological regulation of blood glucose in the following mechanisms, such as the promotion of insulin secretion, inhibition of hepatic glycogenolysis and gluconeogenesis, slows down the decomposition of carbohydrates and promotes the surrounding tissue (such as skeletal muscle and fat cells) to uptake glucose, etc. Results were observed that AFE even had the effect of lowering blood glucose level in mice with hyperglycemia.