LEP and asthma: In a recent review, Kaczyńska et al. demonstrated the involvement of leptin in pulmonary physiology by stimulating the lung ventilation process and in different respiratory diseases; in asthma, leptin increases airway hyperresponsiveness and induces eosinophil accumulation, and in obstructive sleep apnea syndrome, leptin appears to be involved in the apnea-hypopnea index and the incidence of hypercapnia episodes [7].