Tumor growth and initiation were evidently increased in SMMC7221 cells stably overexpressing KIFC1 (SMMC7221-KIFC1) and were decreased in HCCLM3 cells with stable KIFC1 knockdown (HCCLM3-shKIFC1) relative to the corresponding control groups (Figs. 2d, e). The gene discussed is KIFC1; the disease is neoplasm.