By comparing differentially expressed genes in DCM samples with that from healthy controls, we predict that CORIN, FIGF, CTGF, COL1A1, COL1A2, THBS4, THBS4, POSTN, COMP, PRELP and RPS4Y1 may play a role in development of DCM. The gene discussed is COMP; the disease is familial dilated cardiomyopathy.