ITGAM and neoplasm: The radiation-induced release of inflammatory cytokines and chemokines increases tumor infiltration by various leukocytes including not only leukocytes that enhance anti-tumor immune responses, such as DCs, effector T cells, and natural killer (NK) cells [53–55], but also immunosuppressive cells such as regulatory T cells (Treg cells) and CD11b+ cells, including myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) [56–59].