NF1 and malignant peripheral nerve sheath tumor: STS‐26T, S462, and S462‐TY were previously used as transplanted cell strains for MPNST xenograft experiments.38, 39, 40 In advanced MPNST stage, NF1‐associated patients cannot be distinguished from sporadic MPNST patients, indicating that they both ultimately share a similar genetic profile.41 Therefore, in our study, the sporadic MPNST STS‐26T cells were used to establish the xenograft MPNST cancer model.