There are almost all closely related to Alzheimer's disease, oocyte meiosis, Parkinson's disease, oxytocin signaling pathway, cGMP-PKG signaling pathway, tuberculosis, synaptic vesicle cycle, amyotrophic lateral sclerosis (ALS), long-term potentiation (LTP), carbon metabolism, neurotrophin signaling pathway, prion diseases, amphetamine addiction, and glioma. This evidence concerns the gene BDNF and early-onset autosomal dominant Alzheimer disease.