Nano-curcumin attenuated symptoms in EAE MS model, through downregulation of IL-17, NF-κb, and TNF-α receptor expression and upregulation of anti-inflammatory genes and Nrf2, and increased MBP, Olig2, and PDGFR-α expression [403]. The gene discussed is NFKB1; the disease is myeloid sarcoma.