KEGG pathway analysis also indicates that the FGFR1-regulated genes are involved in pathways important for regulating stem cells, inflammation such as the TNF and NF-κB pathways, cancer growth and metastasis such as the NF-κB, hippo, PI3K-Akt, p53, and Ras pathways (Fig. 3c). This evidence concerns the gene AKT1 and cancer.