Bioinformatic analysis of the FGFR1 signaling-regulated genes revealed that these genes are involved in many biological processes, molecular functions, and signaling pathways, including cell proliferation, adhesion and migration, gene regulation, basal cell carcinogenesis, as well as general cancer-promoting pathways such as MAPK, Hippo, PI3K-AKT, Ras, p53, and NF-κB pathways (Fig. 3). This evidence concerns the gene NFKB1 and cancer.