MAPT and dementia: There was also an association between sTREM2 and P-tau levels in the AD biomarker-positive dementia subgroup (β = 0.069, P = 0.004), but not in the AD biomarker-negative subgroup (β = 0.028, P = 0.284) (Fig. 2e), and, in contrast, with Aβ42 levels in the AD biomarker-negative subgroup (β = 0.005, P = 0.002), but not in the AD biomarker-positive subgroup (β = 0.009, P = 0.083) (Fig. 2f).