However, in the dementia group, CSF sTREM2 levels were positively associated with levels of all three markers, after adjusting for age, sex and disease duration: T-tau (β = 0.003, P < 0.001) (Fig. 2a), P-tau (β = 0.038, P = 0.002) (Fig. 2b) and Aβ42 (β = 0.003, P = 0.033) (Fig. 2c). This evidence concerns the gene MAPT and dementia.