In regards to specific markers of NSIP, in comparison to both IPF and normal controls, we identified IFI-44, involved in inflammation and innate immune response pathways [25], and LRP-2 (also known as megalin), a regulator of protein leak during lung injury, highly expressed on the apical surface of epithelial cells [26], as 2 potential candidates, which will require further clinical confirmation. The gene discussed is IFI44; the disease is idiopathic interstitial pneumonia.