The items significant anemia (Hb < 9g/dl), persistent pyrexia(temperature > 38°C for more than 4h), poor peripheral perfusion (coldextremities/ capillary refill > 2 seconds/cool mottled skin), inadequatenutrition, low serum albumin (<35 g/l), weight less than the 10thpercentile, and Incontinence (inappropriate for age) are classified as 0 or 1. The gene discussed is GSTM1; the disease is Urinary incontinence.