EGFR and non-small cell lung carcinoma: During the process of acquired EGFR‐TKI resistance of NSCLC, the epithelial‐to‐mesenchymal transition (EMT) program is considered to be activated, as shown in recent clinical studies.2, 3, 4, 5 For instance, Sequist et al3 analyzed biopsy samples from 37 cases of drug‐resistant NSCLC patients carrying EGFR mutations, and a pronounced EMT was observed in a subset of EGFR‐TKI‐resistant specimens.