While the first two PSMA-RADS-3 classifications have rather low-level uptake, PSMA-RADS-3C sites of uptake are often intense, but in an atypical location for PCa, e.g., an avid lung nodule that is discordant to a patient’s low level of serum prostate-specific antigen. Here, FOLH1 is linked to posterior cortical atrophy.