Furthermore, changes in GLUL and GS levels were assessed in several other gefitinib-resistant NSCLC cell lines (H460, H1299, H1993, H441, H292, and Calu-6) and gefitinib-sensitive NSCLC cell lines (Calu-3 and HCC827), after treatment with equal gefitinib concentration to IC50 value (Supplementary Table S6) Among the gefitinib-resistant cells, except for H460 cells, which were similar to A549 cells and lack of GLUL and GS expression, the other five cell lines expressed GLUL and GS. Here, GLUL is linked to non-small cell lung carcinoma.