The 10 most enriched signaling pathways were dorso-ventral axis formation, renal cell carcinoma, pathways in cancer, MAPK signaling pathway, estrogen signaling pathway, ras signaling pathway, erbB signaling pathway, rap1 signaling pathway, regulation of actin cytoskeleton, and proteoglycans in cancer (Supplementary Fig. S5C). Here, EGFR is linked to renal cell carcinoma.