PPARA and hyperlipidemia: Interestingly, caffeoylquinic acid has been reported for its effect on hyperlipidemia, where the enriching of caffeoylquinic acid derivatives in Pandanus tectorius fruit extract moderated hyperlipidemia and improved the liver lipid profile in hamsters fed high fat diet and these effects may be caused by increasing the expression of PPARα and its downstream genes and by upregulation of LPL and AMPK activities [38].