To investigate whether HIF-1α-induced miR-210 in MM might involve the regulation of cell functions under hypoxic conditions, we studied reduced HIF-1α activity by transfection of cells with a shRNA-anti-HIF-1α (RPMI-8226-anti-HIF-1α); this was undertaken in comparison to cells transfected with pLKO.1 lentiviral vector as negative control cells. The gene discussed is HIF1A; the disease is Miyoshi myopathy.