STAG3 and diabetes mellitus: Interestingly, data from GTEx show that the associated variant is an eQTL for multiple genes in various brain tissues, including STAG3, AGFG2, GAL3ST4, GATS, and PVRIG. In a mouse model of diabetes, microvascular damage in the neurovascular unit of the retina was associated with alteration in STAG3 expression [56].