EGFR and infection: The predicted activation of EGFR and mir-21 signaling early during the infection process, the colocalization of activated EGFR with R. delemar, and the involvement of EGFR in invasion by Candida albicans and diverse microbial pathogens (33, –, 35) compelled us to explore the possibility that EGFR mediates the invasion of airway epithelial cells by R. delemar.