BECN1 and neoplasm: However, decreased Beclin-1 expression was not related to age (older vs. middle aged and youth: OR = 1.01, 95% CI = 0.76–1.35, P = 0.92), gender (male vs. female: OR = 1.11, 95% CI = 0.76–1.63, P = 0.59), liver cirrhosis (positive vs. negative: OR = 1.64, 95% CI = 0.85–3.14, P = 0.14), HBsAg (positive vs. negative: OR = 0.79, 95% CI = 0.45–1.38, P = 0.40), tumor size (> 5 cm vs. ≤ 5 cm: OR = 1.18, 95% CI = 0.88–1.59, P = 0.27), tumor number (multiple vs. solitary: OR = 1.12, 95% CI = 0.77–1.63, P = 0.54), or TNM stage (III–IV vs. I–II: OR = 1.09, 95% CI = 0.72–1.65, P = 0.68).