Mutations in proteins that regulate endocytosis, such as synaptophysin and dynamin 1, have also been linked to neurodevelopmental disorders involving movement abnormalities and EEG disturbance (Ferguson et al., 2007; Tarpey et al., 2009; Gordon et al., 2011; Kwon and Chapman, 2011; von Spiczak et al., 2017). The gene discussed is SYP; the disease is neurodevelopmental disorder.