FAS and fatty liver disease: 2003; Koonen et al. 2007; Ren et al. 2012; Schultz et al. 2012). On the other hand, the current observation that the glucose intolerance and hepatic steatosis were not accompanied with any changes in FAS and OXPHOS protein in the liver is not in accordance with previous studies (Koonen et al. 2007; Nadal‐Casellas et al. 2010; Schultz et al. 2012) and indicates that the diet did not challenge the liver enough to regulate hepatic markers of lipogenic and oxidative capacity.