In both HF and MO eNOS expression was reduced in low‐density fractions compared with LF Mice (% of total in fractions 2–5: Basal LF 74 ± 5%, HF 45 ± 9%*, MO 30 ± 6%*, *P < 0.05 vs. LF) despite persistent localization of cav‐1 to low‐density fractions (Fig. 5A–C). Here, CAV1 is linked to hydrops fetalis.