Among the blood coagulation and fibrinolysis factors tested in the present study, antithrombin III (%) and protein C activity (%) were seemingly lower, and von Willebrand factor activity (%) was seemingly higher when compared with the values in healthy subjects (79–121%, 64–146%, and 60–170%), confirming that CLD patients are at risk of developing PVT, especially after RFA. The gene discussed is VWF; the disease is congenital secretory chloride diarrhea 1.