The recently completed Fourier outcomes trial demonstrated significant reductions in low-density lipoprotein (LDL) cholesterol, nonhigh density lipoprotein (HDL) cholesterol, total cholesterol, Apolipoproteins B (Apo B) and A1, triglycerides, and lipoprotein a in a large population of patients with stable coronary disease using evolocumab [1]. Here, APOB is linked to coronary artery disorder.