To evaluate whether anti-IL-8 or anti-VEGF treatment affected the secretion of other cytokines that may be involved in BCC dissemination, we performed in vitro monolayer co-cultures of E2 stimulated MCF-7 and T47D + BAd or MDA-MB-231 + BAd in the presence of anti-IL-8 or anti-VEGF antibodies. The gene discussed is VEGFA; the disease is skin basal cell carcinoma.