Of these, prominent examples included amplifications targeting the epidermal growth factor receptor (EGFR) (7p11.2) and MYC (8q24.3) and deletions at 10q23.31, encompassing the PTEN tumour suppressor gene in cold tumours and JAK2 (9p24.1) amplifications in hot tumours. This evidence concerns the gene JAK2 and neoplasm.