However, the early detection of MM is not leading to the increase of the period of survival, studies on the molecular pathogenesis and the immunological tumor microenvironment of MM, regarding the role of BRCA1 associated protein 1 (BAP1) and the expression programmed death receptor ligand 1 (PD-L1), are highlighting new and potential therapeutic strategies [89]. The gene discussed is BAP1; the disease is neoplasm.