21/43 (49%) OSCC had >50%, mild, or moderate CD147-positive tumor cells (grade 3 and 4), compared to 9/28 (32%) OSCC with grade 3 or grade 4 staining in adjacent epithelium and only 5/43 (12%) of OSCC cases with that level of staining in the surrounding stroma (p < 0.05, Figure 3B). This evidence concerns the gene BSG and neoplasm.