The PD-L1-positivity was defined as a combined positive score (CPS) ≥1%, where CPS is the number of PD-L1 staining tumor cells, lymphocytes, and macrophages divided by the total number of viable tumor cells multiplied by 100, using PD-L1 Immunohistochemistry (IHC) 22C3 pharmDx immunohistochemistry. Here, CD274 is linked to neoplasm.