Meanwhile, there is also a large body of research demonstrating that overexpression of PRDX1 is a significant indicator of poor prognosis in non-small cell lung cancer [47], hilar cholangiocarcinoma [22], oral squamous cell carcinoma [20], pancreatic cancer [24], hepatocellular carcinoma [48], and rectal cancer [49]. This evidence concerns the gene PRDX1 and rectal cancer.