The mean positive rates of AIB1 expression in lung adenocarcinoma at the localized, regional, and metastatic stages of lung adenocarcinoma were about 20.0%, 40.0%, and 70.0% respectively, compared with 3.0% (range 0.0%–10.0%) for normal tissues (P < 0.001, Fig. 1a–e). Here, NCOA3 is linked to lung adenocarcinoma.