Briefly, dCAR-T cells in mice bearing the cognate tumor cells (AsPC-1) released high levels of cytokines, including 2320 pg/mL IL-2, 609 pg/mL TNFα, 2486 ng/mL IL-6, and 67 ng/mL IFNγ, which was similar to that observed for cytotoxicity. Here, TNF is linked to neoplasm.