Sjögren’s syndrome (SS) is an autoimmune disease characterized by sicca symptoms including xerophthalmia and xerostomia, extraglandular manifestations such as interstitial pneumonia and interstitial nephritis, and the appearance of autoantibodies such as anti-Ro/SS-A, La/SS-B antibodies [1,2,3,4,5]. Here, CALR is linked to Keratoconjunctivitis sicca.