Increasing lines of evidence confirm that MAG controls survival, proliferation, invasion, angiogenesis, metastasis, and chemoresistance of various types of cancers such as bladder cancer, brain cancer, breast cancer, colon cancer, leukemia, liver cancer, lung cancer, ovarian cancer, prostate cancer and skin cancer by regulating multiple signaling pathways (Figure 3). This evidence concerns the gene MAG and skin neoplasm.