Multiple studies on the role of arginine methyltransferases in cellular metabolisms and signalling pathways support their involvement in cancer development, including; (i) cell proliferation—PRMT1, PRMT2, CARM1, PRMT5, PRMT6; PRMT8, PRMT9; (ii) growth stimulation—PRMT1, PRMT2, CARM1, PRMT6; (iii) invasion and metastasis-PRMT1, CARM1, PRMT6; PRMT7, and (iv) angiogenesis-PRMT6 [142]. Here, PRMT5 is linked to cancer.