Chemokines, cytokines, and growth factors commonly secreted in the tumor microenvironment (TME) include the stromal cell-derived factor (SDF1), interleukin-6 (IL-6), interleukin (IL-8), monocyte chemoattractant protein 1 (MCP1), Chemokine (C-C motif) ligand 5 and 7 (CCL5 and CCL7), transforming growth factor-β1 TGF β1, tumor necrosis factor-α (TNFα), fibroblast growth factor (FGF), and others [1,2,3,4]. This evidence concerns the gene CXCL8 and neoplasm.