Lastly, catumaxomab is a humanized antibody that targets three different cell types: tumor cells (via epithelial cell adhesion molecule (EpCAM) binding); T-cells (via CD3 binding); and accessory cells (macrophages, dendritic cells, and natural killer cells) via type I, IIa, and III Fcγ receptors (FcγR). Here, EPCAM is linked to neoplasm.