BMP2 and type 2 diabetes mellitus: In line with this, it has been shown that human monocytes and macrophages undergo M1‐like inflammatory polarization when exposed to high levels of glucose on in vitro culture conditions and in patients with hyperglycaemia, suggesting that increased levels of BMP‐2 in T2DM patients may also contribute to the enhancement of inflammatory responses.37, 38, 39, 40