For this, we used B16F10 murine melanoma cells, as these are able to form VM‐characteristic patterned networks on Matrigel in vitro (supplementary material, Figure S8A) and we have described previously that genetically modified B16F10 cells with elevated PDGF‐B expression (B16F10PDGFB) show enhanced tumor growth in vivo30. The gene discussed is PDGFB; the disease is melanoma.