As one of the important cellular mediators (Patel and Santani 2009; Kolati et al. 2015), NF-κB was found to be up-regulated in the glomeruli and tubules (Vallon 2011; Imig and Ryan 2013), suggesting a close correlation between NF-κB and nephropathy. This evidence concerns the gene NFKB1 and Nephropathy.