BCR and chronic myelogenous leukemia, BCR-ABL1 positive: This study provides evidence to support that, in addition to the BCR-ABL translocation t(9;22) (q34;q11), specific gene abnormalities contribute to the transformation from CML-chronic phase (CML-CP) with no copy number aberrations (CNAs) to CML-blast crisis (CML-BC) in adult and pediatric CML [13–17].