PDGFRB and chronic myelogenous leukemia, BCR-ABL1 positive: At a significance level of p=0.001 and an FDR p value=0.05, 18 genes showed significant down-regulation (p=0.05) among 36 pathways in CML, including the highly significant PDGFR-beta pathway (significance of 3.77 at p=0.000171), the TGF-beta receptor signaling pathway (significance of 3.21 at p=0.000618), the spinal cord injury pathway (significance of 2.56 at p=0.002758), the TGF-beta signaling pathway (significance of 2.44 at p=0.003649), and the MAPK signaling pathway (significance of 1.94 at p=0.011546, Supplementary Table 2b).