CD274 and neoplasm: Moreover, the observation from patient #5 that the high CD3+ TIL content in the tumor biopsy did not reflect a “SUV” content may be that the level of 99mTc-HYNIC-IL2 tumor uptake is reflective of a TIL population that lacks the high-affinity IL2 receptor (activated T cells) and is therefore inactive, potentially as a result of PD1-PDL1 interactions in the TME.