To explore the effects of Lamp2 on the invasiveness of HCC cells, we examined the expression of Lamp2 in six HCC cell lines (SMMC-7721, MHCC97L, Huh7, HepG2, HCCLM3 and MHCC97H) that exhibit different invasive behaviors. The gene discussed is LAMP2; the disease is hepatocellular carcinoma.