AIM2 and psoriasis: Abnormally high levels of IL‐1β could potentiate a T helper type 17 response with up‐regulation of IL‐17 and excessive infiltration of neutrophils, characteristics of psoriatic diseases.115 It is not surprising that AIM2, a receptor involved in the recognition of cytosolic DNA, is involved in psoriatic diseases as cytosolic DNA has been shown to be responsible for inflammasome activation in keratinocytes during psoriasis.116