Whilst a role for variants in GBA in DLB disease risk modulation has been unequivocally established, the role of specific variants in DLB pathogenesis is less clear, due to disparities between studies in classification of GBA variants (analysis restricted to GD variants or also including other rare variants), and differential coverage of the gene (genotyping or whole gene sequencing). Here, GBA1 is linked to Lewy body dementia.