Locus multiplications resulting in three copies (heterozygous duplication) or four copies (homozygous duplication or heterozygous triplication) of SNCA have been described in PD, PDD and DLB [39–44], and a comprehensive review of SNCA mutations in parkinsonism was conducted by Rosborough and colleagues [45]. The gene discussed is SNCA; the disease is Parkinsonism.