AT-rich interactive domain 1A (ARID1A), a component of the BAF complex, has been identified by next-generation sequencing as one of the most frequently mutated genes in a variety of cancers, including ovarian clear cell carcinoma (OCCC)3, gastric cancer4, hepatocellular carcinoma5, esophageal adenocarcinoma6, breast cancer7, pancreatic cancer8 and colorectal cancer (CRC)9. This evidence concerns the gene ARID1A and colorectal cancer.