TNF and cancer: The results from the canonical pathway analysis of the HBx-transfected cells, compared with those of the mock-transfected cells, indicated that a significant number of the DE transcripts was assigned to functional categories of metabolic processes prior to UV irradiation: prostaglandin metabolism, the p53 signaling pathway, TNF signaling pathway, cytokine–cytokine receptor interaction, extracellular matrix–receptor interaction, steroidogenesis, various cancer-related pathways, and the PI3K-Akt signaling pathway.