We also probed the Gn-lip treatment group for several Notch/Wnt downstream targets, as shown in Fig. 7c right panel, Gn-lip treatment led to decreases in MSI1, activated Notch, CYCLIN D1 and SURVIVIN protein levels, indication of decreased Notch/Wnt signaling in the tumor tissues. This evidence concerns the gene BIRC5 and neoplasm.