CALR and cancer: Surface-exposed DAMPs like heat-shock proteins (HSP 70/90), calreticulin (CRT) on cancer cells or secreted DAMPs such as adenosine triphopsphate (ATP), nucleic acids and high mobility group Table 1 protein (HMGB1) interact with respective receptors on DCs and lead to their maturation with upregulation of MHC class II expression [44,45].